Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.43 |
| ▸ | NOS1 | P29475 | 4/20 | 0.43 |
| ▸ | NOS2 | P35228 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26329592 | 0.84 | NOS3 (0.40) | NOS3NOS1NOS2MAPTALDH1A1 | |
| SCHEMBL26329688 | 0.83 | NOS3 (0.37) | NOS3NOS1NOS2MAPTALDH1A1 | |
| SCHEMBL29311726 | 0.81 | NOS3 (0.36) | NOS3NOS1NOS2MAPTALDH1A1 | |
| SCHEMBL18029141 | 0.81 | CRHBP (0.41) | NOS3NOS1NOS2MAPTALDH1A1 | |
| SCHEMBL18000273 | 0.81 | CRHBP (0.41) | NOS3NOS1NOS2MAPTALDH1A1 | |
| SCHEMBL19871246 | 0.78 | MAPT (0.55) | NOS3NOS1NOS2MAPTALDH1A1 | |
| SCHEMBL18029052 | 0.76 | MAPT (0.50) | NOS3NOS1NOS2MAPTALDH1A1 | |
| SCHEMBL20120110 | 0.76 | AURKA (0.42) | MAPTALDH1A1RECQLPKMKDM4E | |
| SCHEMBL18029037 | 0.75 | NR4A2 (0.52) | MAPTALDH1A1RECQL | |
| SCHEMBL26328727 | 0.75 | KMT2A (0.53) | NOS3NOS1NOS2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240229090-A1 | MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-07-11 | — | — | US | disclosed |