Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10953037 | 0.69 | — | — | |
| SCHEMBL29312721 | 0.66 | HTR2A (0.33) | POLQ | |
| SCHEMBL11353 | 0.63 | CYP2A6 (0.44) | — | |
| SCHEMBL2508297 | 0.62 | NOS3 (0.33) | — | |
| SCHEMBL10130898 | 0.61 | GRM5 (0.48) | — | |
| SCHEMBL19992372 | 0.60 | — | — | |
| SCHEMBL20885888 | 0.60 | RECQL (0.34) | — | |
| SCHEMBL174459 | 0.59 | — | — | |
| SCHEMBL23252618 | 0.58 | — | — | |
| Hydrochloric Acid SCHEMBL22436806 | 0.58 | GAA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |