Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | POLQ | O75417 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10130898 | 0.74 | GRM5 (0.48) | HTR2AGRM5 | |
| SCHEMBL20929102 | 0.73 | GRM5 (0.30) | GRM5 | |
| SCHEMBL13723660 | 0.69 | GRM5 (0.43) | HTR2AGRM5 | |
| SCHEMBL29312657 | 0.66 | POLQ (0.34) | POLQ | |
| SCHEMBL13699046 | 0.66 | GRM5 (0.48) | GRM5 | |
| SCHEMBL13722749 | 0.64 | IDH1 (0.41) | GRM5 | |
| SCHEMBL20886074 | 0.63 | — | — | |
| SCHEMBL933581 | 0.63 | NOS3 (0.40) | — | |
| SCHEMBL12500594 | 0.63 | NOS2 (0.46) | — | |
| SCHEMBL31490392 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |