SCHEMBL29312929

SCHEMBL29312929

O=CNC(C=O)Cc1cnc[nH]1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 9/20 0.46
HRH3 Q9Y5N1 9/20 0.46
ALDH1A1 P00352 5/20 0.46
NFKB1 P19838 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
GLA P06280 1/20 0.46
CYP1A2 P05177 1/20 0.46
THPO P40225 1/20 0.46
CYP3A4 P08684 2/20 0.45
SLC7A5 Q01650 1/20 0.45
LMNA P02545 2/20 0.45
APEX1 P27695 2/20 0.45
BLM P54132 1/20 0.45
PKM P14618 1/20 0.40
TSHR P16473 2/20 0.40
GABRA1 P14867 1/20 0.40
GABRR1 P24046 1/20 0.40
GABRR2 P28476 1/20 0.40
GABRA5 P31644 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14213359 0.83 HRH4 (0.50) HRH4HRH3ALDH1A1NFKB1MEN1
SCHEMBL9751643 0.83 HRH3 (0.50) HRH4HRH3ALDH1A1NFKB1MEN1
SCHEMBL17119227 0.83 HRH3 (0.50) HRH4HRH3ALDH1A1NFKB1MEN1
SCHEMBL11117873 0.81 HRH3 (0.47) HRH4HRH3ALDH1A1NFKB1MEN1
SCHEMBL12735917 0.81 HRH4 (0.47) HRH4HRH3ALDH1A1NFKB1MEN1
SCHEMBL17119231 0.81 HRH3 (0.47) HRH4HRH3ALDH1A1NFKB1MEN1
SCHEMBL16557054 0.78 HRH4 (0.41) HRH4HRH3ALDH1A1NFKB1MEN1
SCHEMBL13550919 0.78 HRH4 (0.45) HRH4HRH3ALDH1A1NFKB1MEN1
SCHEMBL13550920 0.77 CYP3A4 (0.47) HRH4HRH3ALDH1A1NFKB1MEN1
SCHEMBL28035475 0.76 CYP3A4 (0.56) ALDH1A1NFKB1CYP1A2CYP3A4SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024147153-A1 PEPTIDE-HISTIDINAL CONJUGATES AS AN ANTI-MALARIAL AGENTS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2024-07-11 WO disclosed