Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313327 | 0.93 | POLQ (0.37) | POLQGAAMAPK1NR1H3SMN1; SMN2 | |
| SCHEMBL29313330 | 0.89 | POLQ (0.39) | POLQGAAMAPK1NR1H3SMN1; SMN2 | |
| SCHEMBL29313263 | 0.86 | POLQ (0.40) | POLQ | |
| SCHEMBL29313294 | 0.86 | POLQ (0.39) | POLQ | |
| SCHEMBL29313293 | 0.85 | POLQ (0.37) | POLQ | |
| SCHEMBL29313435 | 0.85 | POLQ (0.40) | POLQ | |
| SCHEMBL29313298 | 0.84 | POLQ (0.43) | POLQGAAMAPK1NR1H3SMN1; SMN2 | |
| SCHEMBL29313262 | 0.84 | POLQ (0.41) | POLQGAAMAPK1NR1H3SMN1; SMN2 | |
| SCHEMBL29313338 | 0.84 | POLQ (0.35) | POLQ | |
| SCHEMBL29313436 | 0.83 | POLQ (0.40) | POLQGAAMAPK1NR1H3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |