Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19388196 | 0.96 | TSHR (0.36) | TLR8TLR7TSHRKCNA5KCNH2 | |
| SCHEMBL23026166 | 0.76 | APLNR (0.35) | TSHR | |
| SCHEMBL6164383 | 0.73 | TLR8 (0.33) | TLR8TLR7KCNA5KCNH2 | |
| SCHEMBL23754847 | 0.73 | TLR8 (0.32) | TLR8TLR7KCNA5KCNH2 | |
| SCHEMBL18430383 | 0.73 | GRIN2D (0.47) | TSHR | |
| SCHEMBL26828707 | 0.72 | TRPA1 (0.36) | TSHRKCNA5 | |
| SCHEMBL2948062 | 0.71 | KDM4E (0.39) | — | |
| SCHEMBL23844520 | 0.71 | KDM4E (0.41) | TLR8TLR7 | |
| SCHEMBL21564299 | 0.69 | KDM1A (0.35) | TLR8TLR7 | |
| SCHEMBL20610005 | 0.69 | TSHR (0.59) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782986-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-10 | — | — | EP | disclosed |