Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 2/20 | 0.35 |
| ▸ | CCR2 | P41597 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TACR2 | P21452 | 2/20 | 0.31 |
| ▸ | TACR1 | P25103 | 2/20 | 0.31 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313213 | 0.91 | POLQ (0.36) | POLQTACR1 | |
| SCHEMBL29313248 | 0.90 | POLQ (0.34) | POLQCCR2TACR2TACR1 | |
| SCHEMBL29313217 | 0.90 | CCR2 (0.38) | POLQCCR2TACR2TACR1 | |
| SCHEMBL29313218 | 0.88 | TACR1 (0.36) | POLQCCR2TACR1 | |
| SCHEMBL29313254 | 0.88 | POLQ (0.36) | POLQ | |
| SCHEMBL29314250 | 0.85 | CCR2 (0.32) | CCR2KCNH2 | |
| SCHEMBL29313246 | 0.85 | POLQ (0.34) | POLQ | |
| SCHEMBL29313262 | 0.85 | POLQ (0.41) | POLQCCR2TACR1 | |
| SCHEMBL29313340 | 0.84 | POLQ (0.39) | POLQTACR1 | |
| SCHEMBL29313436 | 0.84 | POLQ (0.40) | POLQCCR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |