Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | POLQ | O75417 | 2/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.34 |
| ▸ | CCR2 | P41597 | 3/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 6/20 | 0.31 |
| ▸ | UBE2M | P61081 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313553 | 0.88 | NPY5R (0.39) | HRH3POLQ | |
| SCHEMBL29313500 | 0.87 | POLQ (0.36) | POLQ | |
| SCHEMBL29313440 | 0.85 | POLQ (0.37) | POLQ | |
| SCHEMBL29313554 | 0.84 | POLQ (0.36) | POLQ | |
| SCHEMBL29313248 | 0.84 | POLQ (0.34) | POLQCCR2 | |
| SCHEMBL29313396 | 0.83 | POLQ (0.35) | KCNH2POLQCCR2 | |
| SCHEMBL29313217 | 0.83 | CCR2 (0.38) | POLQCCR2 | |
| SCHEMBL29313399 | 0.83 | POLQ (0.34) | POLQ | |
| SCHEMBL29313218 | 0.82 | TACR1 (0.36) | POLQCCR2 | |
| SCHEMBL29313441 | 0.81 | POLQ (0.41) | POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |