Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28207811 | 1.00 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL119019 | 1.00 | — | — | |
| Bicarbonate SCHEMBL6579968 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL21382654 | 0.94 | — | — | |
| Bicarbonate SCHEMBL7593427 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL14562674 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3876379 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6577630 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL614488 | 0.94 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL5510241 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 603 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12599138-B2 | Cellulosic fibers comprising internally dispersed cuprous oxide nanoparticles | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2026-04-14 | — | — | US | claimed |
| EP-4658401-A1 | ACID WASHING | Calgon Carbon Corporation (US) | 2025-12-10 | — | — | EP | claimed |
| US-20250162188-A1 | WOOD TREATMENT COMPRISING PHOSPHATES | SWIMC LLC | 2025-05-22 | — | — | US | claimed |
| CN-116377507-B | Polymer and copper co-doped coal-based composite material and preparation method and application thereof | 中国矿业大学 | 2025-05-02 | — | — | CN | claimed |
| CN-119869293-A | Copper conductive ink material preparation device and method | 威海蓝湾海洋工程装备研究院有限公司 | 2025-04-25 | — | — | CN | claimed |
| US-12163023-B2 | Camera module | TICONA LLC (US) | 2024-12-10 | — | — | US | claimed |
| EP-4461402-A1 | SORBENT BED FOR AN AIR FILTER | Avon Protection Systems, Inc. (US) | 2024-11-13 | — | — | EP | claimed |
| US-20240326018-A1 | SORBENT BED FOR AN AIR FILTER | AVON PROTECTION SYSTEMS, INC. (US) | 2024-10-03 | — | — | US | claimed |
| US-12059668-B2 | Copper, iron, and nitrogen treated sorbent and method for making same | CALGON CARBON CORPORATION (US) | 2024-08-13 | — | — | US | claimed |
| WO-2024163628-A1 | ACID WASHING | CALGON CARBON CORPORATION (US) | 2024-08-08 | — | — | WO | claimed |
| US-20030104099-A1 | Mineral delivery systems and methods | WM. WRIGLEY JR. COMPANY | 2003-06-05 | — | — | US | claimed |
| US-20030073580-A1 | Composition for treating cells and method for qualitatively and quantitatively customizing the formulation thereof | RUNKIS WALTER H (US) | 2003-04-17 | — | — | US | claimed |
| US-6508995-B1 | Reducing melting temperature by formation of copper, nickel or zinc diamine complex optionally with water inclusion | FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2003-01-21 | — | — | US | claimed |
| WO-2002100772-A2 | COMPOSITION AND METHOD FOR TREATING CELLS AND PLANTS | RUNKIS WALTER H (US) | 2002-12-19 | — | — | WO | claimed |
| EP-0752414-B1 | Process for the production of aromatic urethanes | MINI RICERCA SCIENT TECNOLOG (IT) | 1999-05-06 | — | — | EP | claimed |
| US-5688988-A | REACTION OF AN ORGANIC CARBONATE WITH AROMATIC AMINE USING A ZINC AND/OR COPPER CARBONATE HYDROXIDE CATALYST | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECHNOLOGICA (IT) | 1997-11-18 | — | — | US | claimed |
| EP-0752414-A1 | Process for the production of aromatic urethanes | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1997-01-08 | — | — | EP | claimed |
| US-5312874-A | Poly(benxoic acid), method for the preparation thereof and method for the preparation of poly(p-phenylene) from poly(benzoic acid) | JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1994-05-17 | — | — | US | claimed |
| EP-0566760-A1 | SUPER-CONDUCTING MATERIAL PROCESS FOR THE PREPARATION OF SAME AND USE FOR THE SAID SUPER-CONDUCTING MATERIAL | Sen, Mihir (IN) | 1993-10-27 | — | — | EP | claimed |
| EP-0110387-B1 | HUMIDITY-SENSITIVE ELEMENT AND PROCESS FOR PRODUCING THE SAME | KABUSHIKI KAISHA TOSHIBA (JP) | 1988-03-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12599138-B2 | Cellulosic fibers comprising internally dispersed cuprous oxide nanoparticles | CROCC, CNBP, SOD1 | CA4 520/4885CA1 790/4885FAHD1 4831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.