Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ARG1 | P05089 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314027 | 0.88 | ALDH1A1 (0.55) | ALDH1A1MAPTRECQLARG1KDM4E | |
| SCHEMBL23677906 | 0.85 | ALDH1A1 (0.54) | ALDH1A1MAPTRECQLKDM4EHPGD | |
| SCHEMBL30584520 | 0.85 | ALDH1A1 (0.54) | ALDH1A1MAPTRECQLKDM4EHPGD | |
| SCHEMBL18395823 | 0.85 | ALDH1A1 (0.54) | ALDH1A1MAPTRECQLKDM4EHPGD | |
| SCHEMBL18396286 | 0.85 | MAPT (0.49) | ALDH1A1MAPTRECQLARG1KDM4E | |
| SCHEMBL21747179 | 0.85 | MAPT (0.49) | ALDH1A1MAPTRECQLARG1KDM4E | |
| SCHEMBL18407259 | 0.85 | MAPT (0.49) | ALDH1A1MAPTRECQLARG1KDM4E | |
| SCHEMBL30025033 | 0.85 | MAPT (0.49) | ALDH1A1MAPTRECQLARG1KDM4E | |
| SCHEMBL29314703 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPTRECQLARG1KDM4E | |
| Hydrochloric Acid SCHEMBL22393215 | 0.84 | ALDH1A1 (0.53) | ALDH1A1MAPTRECQLKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226104-A1 | PI3K INHIBITORS, NANOFORMULATIONS, AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226104-A1 | PI3K INHIBITORS, NANOFORMULATIONS, AND USES THEREOF | PI4KA, PIK3CA, PI4KB | ALDH1A1 3641/4885MAPT 1253/4885RECQL 2937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.