Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 5/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 6/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29313937 | 0.82 | POLQ (0.42) | POLQLIPEL3MBTL1 | |
| SCHEMBL29314384 | 0.81 | POLQ (0.52) | POLQLIPEKDM4EALDH1A1NPSR1 | |
| SCHEMBL29314067 | 0.80 | POLQ (0.43) | POLQLIPETLR7 | |
| SCHEMBL29314388 | 0.79 | POLQ (0.50) | POLQLIPEALDH1A1NPSR1TLR7 | |
| SCHEMBL30847596 | 0.79 | POLQ (0.50) | POLQLIPENPSR1TLR7 | |
| SCHEMBL29314044 | 0.77 | POLQ (0.42) | POLQLIPE | |
| SCHEMBL29314375 | 0.76 | POLQ (0.47) | POLQLIPENPSR1TLR7 | |
| SCHEMBL31009186 | 0.73 | POLQ (0.44) | POLQLIPE | |
| SCHEMBL29314374 | 0.73 | POLQ (0.44) | POLQLIPE | |
| SCHEMBL29314065 | 0.73 | POLQ (0.44) | POLQLIPENPSR1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |