Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 6/20 | 0.52 |
| ▸ | LIPE | Q05469 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314388 | 0.90 | POLQ (0.50) | POLQLIPELMNAALDH1A1GAA | |
| SCHEMBL30847596 | 0.88 | POLQ (0.50) | POLQLIPELMNAGAARAB9A | |
| SCHEMBL30847641 | 0.86 | POLQ (0.43) | POLQLIPELMNAALDH1A1KDM4E | |
| SCHEMBL29314831 | 0.85 | POLQ (0.42) | POLQLMNAALDH1A1KDM4ENPC1 | |
| SCHEMBL29314375 | 0.85 | POLQ (0.47) | POLQLIPELMNARAB9AHTT | |
| SCHEMBL29315012 | 0.84 | POLQ (0.41) | POLQLMNAALDH1A1KDM4ENPC1 | |
| SCHEMBL31009186 | 0.81 | POLQ (0.44) | POLQLIPE | |
| SCHEMBL29314065 | 0.81 | POLQ (0.44) | POLQLIPELMNAHTTNPSR1 | |
| SCHEMBL29314374 | 0.81 | POLQ (0.44) | POLQLIPE | |
| SCHEMBL29314066 | 0.81 | POLQ (0.43) | POLQLIPEALDH1A1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |