Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4578984 | 0.77 | CTSK (0.42) | CHEK1CTSKALDH1A1HPGDALOX12 | |
| SCHEMBL29316281 | 0.76 | LRRK2 (0.40) | PLK1LRRK2JAK2JAK3 | |
| SCHEMBL29313602 | 0.71 | POLB (0.48) | ALDH1A1HPGDPOLBKDM4ESIRT5 | |
| SCHEMBL4579364 | 0.71 | SMN1; SMN2 (0.45) | CTSKALDH1A1HPGDALOX12HTT | |
| SCHEMBL23019442 | 0.68 | LRRK2 (0.36) | PLK1LRRK2 | |
| SCHEMBL11160250 | 0.67 | MAPT (0.47) | ALDH1A1HPGDFGFR4KDM4EMEN1 | |
| SCHEMBL29313990 | 0.66 | CHEK1 (0.40) | CHEK1PLK1LRRK2JAK2JAK3 | |
| SCHEMBL4768640 | 0.65 | POLB (0.49) | ALDH1A1HPGDHTTPOLBLRRK2 | |
| SCHEMBL23019450 | 0.65 | PLK1 (0.40) | PLK1FGFR4LRRK2 | |
| SCHEMBL29313687 | 0.65 | POLB (0.41) | CHEK1ALDH1A1HPGDPOLBLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782986-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-10 | — | — | EP | disclosed |