Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.40 |
| ▸ | MERTK | Q12866 | 13/20 | 0.39 |
| ▸ | AXL | P30530 | 12/20 | 0.39 |
| ▸ | FLT3 | P36888 | 12/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22475664 | 0.86 | MET (0.40) | METMERTKAXLFLT3KEAP1 | |
| SCHEMBL22109646 | 0.86 | MET (0.40) | METMERTKAXLFLT3KEAP1 | |
| SCHEMBL29317783 | 0.85 | MET (0.41) | METMERTKAXLFLT3KEAP1 | |
| SCHEMBL29317548 | 0.83 | MET (0.37) | METDYRK1A | |
| SCHEMBL22475770 | 0.83 | MET (0.55) | METMERTKAXLFLT3KEAP1 | |
| SCHEMBL29316180 | 0.80 | KEAP1 (0.37) | METMERTKAXLFLT3KEAP1 | |
| SCHEMBL22109432 | 0.79 | MET (0.42) | METMERTKAXLFLT3KEAP1 | |
| SCHEMBL22109398 | 0.79 | MERTK (0.39) | METMERTKAXLFLT3KEAP1 | |
| SCHEMBL16882493 | 0.77 | MERTK (0.44) | METMERTKAXLFLT3KEAP1 | |
| SCHEMBL22475991 | 0.76 | MET (0.40) | METMERTKAXLFLT3KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |