Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.38 |
| ▸ | FLT3 | P36888 | 4/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.38 |
| ▸ | PRKACA | P17612 | 2/20 | 0.38 |
| ▸ | LTK | P29376 | 2/20 | 0.38 |
| ▸ | GRK5 | P34947 | 2/20 | 0.38 |
| ▸ | CDK8 | P49336 | 2/20 | 0.38 |
| ▸ | CDK7 | P50613 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.38 |
| ▸ | MST1R | Q04912 | 2/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8404487 | 0.79 | CYP1A2 (0.41) | KDRFLT3AURKBMAP4K4PDGFRB | |
| SCHEMBL25591524 | 0.79 | KDR (0.37) | KDRFLT3AURKBMAP4K4PDGFRB | |
| SCHEMBL28133259 | 0.76 | LMNA (0.47) | KDRFLT3AURKBMAP4K4PDGFRB | |
| SCHEMBL21807299 | 0.76 | KDR (0.38) | KDRFLT3AURKBMAP4K4PDGFRB | |
| SCHEMBL21783714 | 0.76 | KDR (0.45) | KDRFLT3AURKBMAP4K4PDGFRB | |
| SCHEMBL28133272 | 0.76 | KDR (0.38) | KDRFLT3AURKBMAP4K4PDGFRB | |
| SCHEMBL3195416 | 0.76 | KCNA5 (0.46) | KDRFLT3AURKBMAP4K4PDGFRB | |
| SCHEMBL25833612 | 0.73 | KCNA5 (0.49) | KDRFLT3AURKBMAP4K4PDGFRB | |
| SCHEMBL13305129 | 0.73 | KCNA5 (0.38) | KDRFLT3AURKBMAP4K4PDGFRB | |
| SCHEMBL25832889 | 0.73 | LMNA (0.38) | KDRFLT3AURKBMAP4K4PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400499-A1 | GLUTARIMIDE COMPOUND AND USE THEREOF | Medshine Discovery Inc. (CN) | 2024-07-17 | — | — | EP | disclosed |