Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 5/20 | 0.42 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21807407 | 0.84 | PDCD1 (0.37) | KCNA5SGMS1SGMS2CHEK1MAP4K4 | |
| SCHEMBL19695714 | 0.80 | KDR (0.50) | KCNA5ELANECHEK1MAP4K4ABL1 | |
| SCHEMBL8404487 | 0.76 | CYP1A2 (0.41) | ELANESGMS1SGMS2CHEK1MAP4K4 | |
| SCHEMBL6830612 | 0.76 | KCNA5 (0.48) | KCNA5ELANESGMS1SGMS2GABRA1 | |
| SCHEMBL30422301 | 0.75 | KCNA5 (0.44) | KCNA5ELANESGMS1SGMS2GABRA1 | |
| SCHEMBL22864075 | 0.75 | KCNA5 (0.39) | KCNA5SGMS1SGMS2CHEK1MAP4K4 | |
| SCHEMBL21807299 | 0.73 | KDR (0.38) | CHEK1MAP4K4ABL1NTRK1LCK | |
| SCHEMBL21783714 | 0.73 | KDR (0.45) | CHEK1MAP4K4ABL1NTRK1LCK | |
| SCHEMBL29314341 | 0.73 | KDR (0.38) | KCNA5CHEK1MAP4K4ABL1NTRK1 | |
| SCHEMBL3195416 | 0.73 | KCNA5 (0.46) | KCNA5CHEK1MAP4K4ABL1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219947-A1 | INHIBITORS OF AV ß6 INTEGRIN | MORPHIC THERAPEUTIC, INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219947-A1 | INHIBITORS OF AV ß6 INTEGRIN | ITGB6, ITGA6, GP6 | KCNA5 765/4885ELANE 763/4885SGMS1 1977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.