Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 8/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23037521 | 0.95 | NAMPT (0.37) | NAMPTTLR8TLR7HDAC6HDAC3 | |
| SCHEMBL30539908 | 0.95 | NAMPT (0.37) | NAMPTTLR8TLR7HDAC6HDAC3 | |
| SCHEMBL26783689 | 0.89 | NAMPT (0.36) | NAMPTHDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL29314757 | 0.88 | TLR8 (0.40) | TLR8TLR7 | |
| SCHEMBL29314678 | 0.87 | MAOB (0.38) | NAMPTTLR8TLR7MAPT | |
| SCHEMBL29314715 | 0.86 | MAPT (0.36) | NAMPTTLR8TLR7MAPTABL1 | |
| SCHEMBL29314664 | 0.86 | SCN9A (0.39) | — | |
| SCHEMBL29314671 | 0.85 | BACE1 (0.35) | NAMPTMAPT | |
| SCHEMBL29314661 | 0.85 | CFTR (0.40) | NAMPTTLR8TLR7MAPT | |
| SCHEMBL23037613 | 0.85 | NTRK1 (0.35) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037344-B2 | NLRP3 modulators | INNATE TUMOR IMMUNITY, INC (US) | 2024-07-16 | — | — | US | disclosed |
| US-12037344-B2 | NLRP3 modulators | INNATE TUMOR IMMUNITY, INC (US) | 2024-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12037344-B2 | NLRP3 modulators | NLRP3, NLRP1, PYCARD | NAMPT 122/4885TLR8 210/4885TLR7 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.