SCHEMBL29314967

SCHEMBL29314967

CCOP(C)(=O)Cc1ccc(-c2cnc(N)c(N(N)C(C)(C)c3ccc4ncccc4c3)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MET P08581 14/20 0.37
ATR Q13535 1/20 0.35
HDAC1 Q13547 2/20 0.35
SRC P12931 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29317711 0.85 MET (0.41) METATRHDAC1
SCHEMBL29314794 0.82 MET (0.39) METATRHDAC1
SCHEMBL29315062 0.81 MET (0.41) METATRHDAC1
SCHEMBL29314740 0.78 MET (0.41) METATRHDAC1
SCHEMBL29314116 0.78 MET (0.41) METATR
SCHEMBL29314974 0.76 MET (0.47) MET
SCHEMBL29314872 0.76 MET (0.37) METATRHDAC1
SCHEMBL22109187 0.74 MET (0.49) MET
SCHEMBL29314999 0.73 ATR (0.40) METATRSRC
SCHEMBL29317734 0.73 MET (0.43) METATR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3893872-B1 ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF BETA PHARMA INC (US) 2024-07-17 EP disclosed