Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.60 |
| ▸ | NQO2 | P16083 | 1/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22109153 | 0.92 | MET (0.72) | METNQO2PDE4CPDE4DPDE3B | |
| SCHEMBL29314927 | 0.84 | MET (0.56) | METNQO2PDE4CPDE4DPDE3B | |
| SCHEMBL22109361 | 0.81 | MET (0.58) | METNQO2PDE4CPDE4DPDE3B | |
| SCHEMBL22109435 | 0.81 | MET (0.74) | METNQO2PDE3BPDE3A | |
| SCHEMBL12689735 | 0.80 | MET (0.78) | METNQO2PDE4CPDE4DPDE3B | |
| SCHEMBL22109380 | 0.80 | MET (0.55) | METNQO2PDE4CPDE4DPDE3B | |
| SCHEMBL12489197 | 0.77 | MET (0.73) | METNQO2PDE4CPDE4DPDE3B | |
| Savolitinib SCHEMBL12489208 | 0.75 | MET (1.00) | METNQO2PDE4CPDE4DPDE3B | |
| Savolitinib SCHEMBL12690037 | 0.75 | MET (1.00) | METNQO2PDE4CPDE4DPDE3B | |
| Savolitinib SCHEMBL12486932 | 0.75 | MET (1.00) | METNQO2PDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |