Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 14/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 14/20 | 0.41 |
| ▸ | CDK2 | P24941 | 14/20 | 0.41 |
| ▸ | CDK9 | P50750 | 14/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 8/20 | 0.41 |
| ▸ | CDK1 | P06493 | 9/20 | 0.39 |
| ▸ | KDR | P35968 | 5/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.37 |
| ▸ | CDK7 | P50613 | 5/20 | 0.37 |
| ▸ | CCNH | P51946 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314750 | 0.82 | HSP90AB1 (0.39) | HSP90AB1CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL22998096 | 0.78 | HSP90AB1 (0.41) | HSP90AB1 | |
| SCHEMBL13523666 | 0.74 | KDM4E (0.41) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL23019360 | 0.74 | KDR (0.41) | HSP90AB1CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL21410027 | 0.73 | HSP90AB1 (0.38) | HSP90AB1 | |
| SCHEMBL21549440 | 0.72 | CDK7 (0.57) | CCNT1CDK2CDK9CDK1KDR | |
| SCHEMBL22684859 | 0.70 | CCNT1 (0.54) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL29315387 | 0.70 | KDR (0.37) | HSP90AB1CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL29314779 | 0.70 | BRD4 (0.42) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL29314680 | 0.70 | KDR (0.45) | CCNT1CCNA2CDK2CDK9CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782986-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-10 | — | — | EP | disclosed |