Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29315693 | 0.98 | NPC1 (0.42) | NPC1LMNARAB9AHDAC6TDP1 | |
| SCHEMBL29315692 | 0.96 | NPC1 (0.44) | NPC1LMNARAB9AHDAC6ESR1 | |
| SCHEMBL31361789 | 0.90 | HDAC6 (0.51) | NPC1LMNARAB9AHDAC6TDP1 | |
| SCHEMBL6741249 | 0.90 | HDAC6 (0.51) | NPC1LMNARAB9AHDAC6TDP1 | |
| SCHEMBL24089437 | 0.89 | HDAC6 (0.38) | HDAC6TDP1ESR1ALDH1A1CYP3A4 | |
| SCHEMBL29315717 | 0.87 | NPC1 (0.39) | NPC1LMNARAB9AHDAC6ALDH1A1 | |
| SCHEMBL29315676 | 0.86 | THRB (0.46) | NPC1LMNARAB9ATDP1ALDH1A1 | |
| SCHEMBL24089270 | 0.85 | HDAC6 (0.44) | NPC1LMNARAB9AHDAC6ESR1 | |
| SCHEMBL24089435 | 0.85 | THRB (0.40) | NPC1LMNARAB9AESR1ALDH1A1 | |
| SCHEMBL25408635 | 0.85 | LMNA (0.42) | NPC1LMNARAB9AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239934-A1 | FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE | TOSOH CORPORATION (JP) | 2024-07-18 | — | — | US | disclosed |
| US-20240239934-A1 | FUMARIC ACID DIESTER RESIN, FILM AND POLARIZING PLATE | TOSOH CORPORATION (JP) | 2024-07-18 | — | — | US | disclosed |