Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29315748 | 0.90 | LRRK2 (0.39) | LRRK2IRAK4MBOAT4PRKCQPRKCD | |
| SCHEMBL29315949 | 0.80 | LRRK2 (0.48) | LRRK2IRAK4PRKCQPRKCDCYP2C9 | |
| SCHEMBL30662127 | 0.79 | CSNK1A1 (0.45) | LRRK2IRAK4ALDH1A1ACHE | |
| SCHEMBL21409882 | 0.79 | CSNK1A1 (0.45) | LRRK2IRAK4ALDH1A1ACHE | |
| SCHEMBL8595874 | 0.77 | ACHE (0.42) | LRRK2MBOAT4PRKCQPRKCDACHE | |
| SCHEMBL29316281 | 0.74 | LRRK2 (0.40) | LRRK2IRAK4PRKCQPRKCDCYP2C9 | |
| SCHEMBL21066963 | 0.68 | PRKCQ (0.39) | LRRK2PRKCQALDH1A1ACHE | |
| SCHEMBL13736333 | 0.68 | NPSR1 (0.44) | LRRK2PRKCQALDH1A1KDM4EHPGD | |
| SCHEMBL14657063 | 0.68 | LRRK2 (0.50) | LRRK2IRAK4PRKCQPRKCDCYP2C9 | |
| SCHEMBL21162418 | 0.68 | LRRK2 (0.50) | LRRK2IRAK4PRKCQPRKCDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782986-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2024-07-10 | — | — | EP | disclosed |