Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HRH2 | P25021 | 3/20 | 0.35 |
| ▸ | HRH1 | P35367 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15908130 | 0.89 | CYP1A2 (0.39) | POLBSMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL20943327 | 0.82 | POLB (0.57) | POLBSMN1; SMN2LMNAHTTTHRB | |
| SCHEMBL22018193 | 0.82 | POLB (0.57) | POLBSMN1; SMN2LMNAHTTTHRB | |
| SCHEMBL21428430 | 0.80 | POLB (0.58) | POLBSMN1; SMN2LMNAHTTTHRB | |
| SCHEMBL5594524 | 0.78 | POLB (0.65) | POLBSMN1; SMN2LMNAHTTCYP1A2 | |
| SCHEMBL10530748 | 0.77 | POLB (0.46) | POLBSMN1; SMN2LMNAHTTAPP | |
| SCHEMBL15934122 | 0.76 | TDP1 (0.43) | POLBSMN1; SMN2LMNAHTTMAPT | |
| SCHEMBL15934091 | 0.76 | KDM4E (0.44) | POLBSMN1; SMN2LMNAHTTMAPT | |
| SCHEMBL14438140 | 0.75 | ALDH1A1 (0.45) | POLBSMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL6129170 | 0.74 | POLB (0.64) | POLBSMN1; SMN2LMNAHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400168-A2 | ANTISENSE NUCLEIC ACIDS | Nippon Shinyaku Co., Ltd. (JP) | 2024-07-17 | — | — | EP | disclosed |