Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.45 |
| ▸ | HRH1 | P35367 | 4/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29316597 | 0.94 | MCHR1 (0.49) | KDM4ENPC1RAB9AGFERSMN1; SMN2 | |
| SCHEMBL29316658 | 0.90 | HDAC4 (0.44) | KDM4ENPC1RAB9AGFERSMN1; SMN2 | |
| SCHEMBL29316797 | 0.90 | MCHR1 (0.51) | NPC1RAB9AMCHR1ADRA2AHRH1 | |
| SCHEMBL29316888 | 0.89 | CYP3A4 (0.47) | NPC1RAB9ASMN1; SMN2MCHR1ADRA2A | |
| SCHEMBL24512958 | 0.87 | MLYCD (0.45) | KDM4EGFERHDAC4GRM5TAS1R3 | |
| SCHEMBL29316779 | 0.87 | NPC1 (0.51) | NPC1RAB9AMCHR1ADRA2AHRH1 | |
| SCHEMBL29665947 | 0.87 | MCHR1 (0.51) | KDM4ENPC1RAB9AGFERSMN1; SMN2 | |
| SCHEMBL24632297 | 0.87 | MCHR1 (0.51) | KDM4ENPC1RAB9AGFERSMN1; SMN2 | |
| SCHEMBL29316827 | 0.86 | MCHR1 (0.44) | KDM4ENPC1RAB9AGFERSMN1; SMN2 | |
| SCHEMBL29317030 | 0.86 | SMYD3 (0.54) | NPC1RAB9AHDAC4ARHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239749-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS AND METHODS | ESCIENT PHARMACEUTICALS INC (US) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239749-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS AND METHODS | MRGPRX2, MRGPRX1, MRGPRX4 | KDM4E 4624/4885NPC1 2243/4885RAB9A 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.