Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 17/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.69 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.69 |
| ▸ | PPARG | P37231 | 2/20 | 0.64 |
| ▸ | PPARD | Q03181 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19503865 | 0.86 | ADORA3 (0.76) | ADORA3ADORA2AADORA1ADORA2BPPARG | |
| SCHEMBL7074656 | 0.82 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2BPPARG | |
| SCHEMBL19807419 | 0.82 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2BPPARG | |
| SCHEMBL19459779 | 0.82 | ADORA3 (1.00) | ADORA3ADORA2AADORA1ADORA2BPPARG | |
| SCHEMBL4350082 | 0.81 | ADORA3 (0.73) | ADORA3ADORA2AADORA1ADORA2BPPARG | |
| SCHEMBL19503344 | 0.80 | ADORA3 (0.64) | ADORA3ADORA2AADORA1 | |
| SCHEMBL4354401 | 0.80 | ADORA3 (0.70) | ADORA3ADORA2AADORA1ADORA2BPPARG | |
| SCHEMBL4350110 | 0.79 | ADORA3 (0.66) | ADORA3ADORA2AADORA1PPARGPPARD | |
| SCHEMBL5369601 | 0.79 | ADORA3 (0.75) | ADORA3ADORA2AADORA1ADORA2BPPARG | |
| SCHEMBL14325238 | 0.79 | ADORA3 (0.75) | ADORA3ADORA2AADORA1ADORA2BPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445368-B1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS INC (US) | 2024-07-17 | — | — | EP | disclosed |