Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5228670 | 0.77 | HTR6 (0.57) | HTR6SLC6A1SLC6A11TSHRLMNA | |
| SCHEMBL20757788 | 0.77 | HTR6 (0.57) | HTR6SLC6A1SLC6A11TSHRLMNA | |
| SCHEMBL20757771 | 0.77 | HTR6 (0.57) | HTR6SLC6A1SLC6A11TSHRLMNA | |
| SCHEMBL20744481 | 0.76 | HTR6 (0.72) | HTR6SLC6A1SLC6A11TSHRLMNA | |
| SCHEMBL12730878 | 0.76 | HTR6 (0.72) | HTR6SLC6A1SLC6A11TSHRLMNA | |
| SCHEMBL20744604 | 0.76 | HTR6 (0.79) | HTR6SLC6A1SLC6A11TSHRLMNA | |
| SCHEMBL2328636 | 0.76 | HTR6 (0.79) | HTR6SLC6A1SLC6A11TSHRLMNA | |
| Hydrochloric Acid SCHEMBL31015226 | 0.75 | HTR6 (0.55) | HTR6SLC6A1SLC6A11TSHRLMNA | |
| SCHEMBL20757922 | 0.74 | HTR6 (0.59) | HTR6SLC6A1SLC6A11TSHRLMNA | |
| SCHEMBL20757921 | 0.74 | HTR6 (0.59) | HTR6SLC6A1SLC6A11TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |