Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 14/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24615060 | 0.82 | ADORA3 (0.76) | ADORA3ADORA1CYP1A2 | |
| SCHEMBL13400311 | 0.80 | ADORA3 (0.69) | ADORA3ADORA1ADORA2ACYP1A2 | |
| SCHEMBL935050 | 0.80 | ADORA3 (0.83) | ADORA3ADORA1 | |
| SCHEMBL19520735 | 0.80 | ADORA3 (0.69) | ADORA3ADORA1 | |
| SCHEMBL29389782 | 0.80 | ADORA3 (0.83) | ADORA3ADORA1 | |
| SCHEMBL24838613 | 0.79 | ADORA3 (0.60) | ADORA3ADORA1ADORA2A | |
| SCHEMBL21710887 | 0.74 | ADORA3 (0.52) | ADORA3ADORA1ADORA2A | |
| SCHEMBL7512284 | 0.73 | ADORA3 (0.69) | ADORA3ADORA1ADORA2A | |
| SCHEMBL937053 | 0.73 | ADORA3 (0.73) | ADORA3ADORA1ADORA2A | |
| SCHEMBL640073 | 0.73 | ADORA3 (0.80) | ADORA3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445368-B1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS INC (US) | 2024-07-17 | — | — | EP | disclosed |