Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | DHCR7 | Q9UBM7 | 3/20 | 0.36 |
| ▸ | EBP | Q15125 | 2/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310092 | 0.87 | KDM4E (0.41) | KDM4EPOLBL3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL14628353 | 0.85 | KDM4E (0.43) | KDM4EPOLBL3MBTL3L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL310595 | 0.85 | KDM4E (0.40) | KDM4EPOLBL3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL4475326 | 0.85 | L3MBTL3 (0.49) | L3MBTL3L3MBTL1GNAI3GNAO1GNAI1 | |
| SCHEMBL21931367 | 0.85 | KDM4E (0.47) | KDM4EPOLBALDH1A1ALOX15DHCR7 | |
| Hydrochloric Acid SCHEMBL28757439 | 0.83 | L3MBTL3 (0.47) | L3MBTL3L3MBTL1GNAI3GNAO1GNAI1 | |
| SCHEMBL30359096 | 0.80 | KDM4E (0.40) | KDM4EPOLBL3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL22595374 | 0.80 | HTR6 (0.38) | KDM4EPOLBL3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL26118274 | 0.80 | KDM4E (0.47) | KDM4EPOLBALDH1A1ALOX15DHCR7 | |
| SCHEMBL82615 | 0.80 | KDM4E (0.47) | KDM4EPOLBALDH1A1ALOX15DHCR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |