Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 5/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30057144 | 1.00 | FGFR1 (0.37) | FGFR1KDRCDK5GSK3AGSK3B | |
| SCHEMBL27167139 | 0.77 | CDK5 (0.36) | FGFR1KDRCDK5GSK3AGSK3B | |
| SCHEMBL24192115 | 0.75 | CHEK1 (0.39) | FGFR1KDRCDK5GSK3AGSK3B | |
| SCHEMBL26326289 | 0.74 | HTR2A (0.36) | FGFR1KDRCDK5GSK3AGSK3B | |
| SCHEMBL30368490 | 0.74 | HTR2A (0.36) | FGFR1KDRCDK5GSK3AGSK3B | |
| SCHEMBL2782735 | 0.73 | GSK3B (0.40) | FGFR1KDRCDK5GSK3AGSK3B | |
| SCHEMBL18721844 | 0.73 | FGFR1 (0.36) | FGFR1KDRCDK5GSK3AGSK3B | |
| SCHEMBL24683458 | 0.71 | SMYD3 (0.40) | FGFR1KDRCDK5GSK3AGSK3B | |
| SCHEMBL580431 | 0.69 | CDK5 (0.47) | FGFR1KDRCDK5GSK3AGSK3B | |
| SCHEMBL260293 | 0.69 | TNNI3K (0.39) | FGFR1KDRCDK5GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260035367-A1 | PKC-Theta Modulators | CELGENE CORPORATION (US) | 2026-02-05 | — | — | US | disclosed |
| US-20240239794-A1 | PKC-Theta Modulators | EXSCIENTIA AI LIMITED (GB) | 2024-07-18 | — | — | US | disclosed |
| US-20240239794-A1 | PKC-Theta Modulators | EXSCIENTIA AI LIMITED (GB) | 2024-07-18 | — | — | US | disclosed |
| US-20240239794-A1 | PKC-Theta Modulators | EXSCIENTIA AI LIMITED (GB) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239794-A1 | PKC-Theta Modulators | PRKCQ, PRKCH, PRKCZ | FGFR1 4281/4885KDR 4131/4885CDK5 291/4885 |
| US-20260035367-A1 | PKC-Theta Modulators | PRKAR2B, PRKAR2A, PRKCD | FGFR1 3411/4885KDR 1648/4885CDK5 892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.