Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL824892 | 1.00 | DPP4 (0.42) | DPP4AGTR2ATMTSHRPIK3CA | |
| SCHEMBL14995124 | 0.83 | — | — | |
| Nitric Acid SCHEMBL10640882 | 0.83 | DPP4 (0.38) | DPP4AGTR2ATMPIK3CAPIK3CD | |
| SCHEMBL25733592 | 0.82 | PIK3CA (0.42) | DPP4AGTR2ATMTSHRPIK3CA | |
| SCHEMBL19867145 | 0.82 | PIK3CA (0.42) | DPP4AGTR2ATMTSHRPIK3CA | |
| SCHEMBL11687472 | 0.81 | KCNH2 (0.51) | — | |
| SCHEMBL351195 | 0.78 | DPP4 (0.46) | DPP4AGTR2ATMTSHRPIK3CA | |
| SCHEMBL13634926 | 0.78 | PIK3CA (0.44) | DPP4AGTR2ATMTSHRPIK3CA | |
| SCHEMBL14645846 | 0.78 | GRIN2D (0.46) | DPP4AGTR2PIK3CAPIK3CDPIK3CB | |
| SCHEMBL6174357 | 0.77 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTNPSR1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239805-A1 | AZA-YANG CYCLIZATION-BUCHNER AROMATIC RING EXPANSION: COLLECTIVE SYNTHESIS OF CYCLOHEPTATRIENE-CONTAINING AZETIDINE LACTONES | UNIVERSITY OF KANSAS | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239805-A1 | AZA-YANG CYCLIZATION-BUCHNER AROMATIC RING EXPANSION: COLLECTIVE SYNTHESIS OF CYCLOHEPTATRIENE-CONTAINING AZETIDINE LACTONES | AZI2, NISCH, TET2 | DPP4 2919/4885AGTR2 191/4885ATM 2863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.