Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634926 | 0.80 | PIK3CA (0.44) | DPP4AGTR2TSHRPIK3CAPIK3CD | |
| SCHEMBL14645771 | 0.80 | DPP4 (0.57) | DPP4AGTR2HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL14646637 | 0.80 | DPP4 (0.57) | DPP4AGTR2HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL14995124 | 0.79 | — | — | |
| SCHEMBL824892 | 0.78 | DPP4 (0.42) | DPP4AGTR2TSHRPIK3CAPIK3CD | |
| SCHEMBL29317145 | 0.78 | DPP4 (0.42) | DPP4AGTR2TSHRPIK3CAPIK3CD | |
| SCHEMBL25733592 | 0.78 | PIK3CA (0.42) | DPP4AGTR2TSHRPIK3CAPIK3CD | |
| SCHEMBL19867145 | 0.78 | PIK3CA (0.42) | DPP4AGTR2TSHRPIK3CAPIK3CD | |
| SCHEMBL17275232 | 0.77 | DPP4 (0.55) | DPP4AGTR2HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL19468226 | 0.77 | DPP4 (0.49) | DPP4AGTR2HCRTR1HCRTR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015947-A1 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| US-20120015947-A1 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| US-20120015947-A1 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| US-8053432-B2 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2011-11-08 | — | — | US | disclosed |
| US-8053432-B2 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2011-11-08 | — | — | US | disclosed |
| US-8053432-B2 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2011-11-08 | — | — | US | disclosed |
| US-7842690-B2 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2010-11-30 | — | — | US | disclosed |
| US-7842689-B2 | suitable for the treatment of anxiety and depression; 2-(4-hydroxymorpholin-3-yl)cyclohex-2-en-1-one; anxiolytic agents; antidepressants | BTG INTERNATIONAL LIMITED (GB) | 2010-11-30 | — | — | US | disclosed |
| US-7842689-B2 | suitable for the treatment of anxiety and depression; 2-(4-hydroxymorpholin-3-yl)cyclohex-2-en-1-one; anxiolytic agents; antidepressants | BTG INTERNATIONAL LIMITED (GB) | 2010-11-30 | — | — | US | disclosed |
| US-7842689-B2 | suitable for the treatment of anxiety and depression; 2-(4-hydroxymorpholin-3-yl)cyclohex-2-en-1-one; anxiolytic agents; antidepressants | BTG INTERNATIONAL LIMITED (GB) | 2010-11-30 | — | — | US | disclosed |
| US-20100256150-A1 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2010-10-07 | — | — | US | disclosed |
| US-20100256150-A1 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2010-10-07 | — | — | US | disclosed |
| CN-1805944-B | Cyclic hydroxylamine as psychoactive compounds | BRITISH TECH GROUP INT | 2010-06-16 | — | — | CN | disclosed |
| US-20090312329-A1 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2009-12-17 | — | — | US | disclosed |
| US-20090312329-A1 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2009-12-17 | — | — | US | disclosed |
| US-20090312329-A1 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2009-12-17 | — | — | US | disclosed |
| EP-1631557-B1 | CYCLIC HYDROXYLAMINE AS PSYCHOACTIVE COMPOUNDS | BTG INT LTD (GB) | 2006-12-20 | — | — | EP | disclosed |
| CN-1805944-A | Cyclic hydroxylamine as psychoactive compounds | BTG INT LTD (GB) | 2006-07-19 | — | — | CN | disclosed |
| US-20060142286-A1 | Cyclic hydroxylamine as psychoactive compounds | BTG INTERNATIONAL LIMITED (GB) | 2006-06-29 | — | — | US | disclosed |
| WO-2004111021-A1 | CYCLIC HYDROXYLAMINE AS PSYCHOACTIVE COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015947-A1 | Cyclic hydroxylamine as psychoactive compounds | HTR1A, HTR1D, OPRM1 | DPP4 4798/4885AGTR2 739/4885TSHR 487/4885 |
| US-20090312329-A1 | Cyclic hydroxylamine as psychoactive compounds | HTR1A, HTR2C, OPRM1 | DPP4 4711/4885AGTR2 905/4885TSHR 520/4885 |
| US-20100256150-A1 | Cyclic hydroxylamine as psychoactive compounds | HTR1A, HTR2C, OPRM1 | DPP4 4711/4885AGTR2 905/4885TSHR 520/4885 |
| US-20060142286-A1 | Cyclic hydroxylamine as psychoactive compounds | HTR1A, HTR2C, OPRM1 | DPP4 4711/4885AGTR2 905/4885TSHR 520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.