Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 11/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.34 |
| ▸ | USP2 | O75604 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24233213 | 0.82 | TSHR (0.36) | CYP2D6CYP3A4ALDH1A1CYP2C19TSHR | |
| SCHEMBL29317411 | 0.80 | POLB (0.35) | SMN1; SMN2HRH3TLR9TLR8TLR7 | |
| SCHEMBL29317112 | 0.78 | CYP2D6 (0.50) | CYP2D6CYP3A4ALDH1A1CYP2C19TSHR | |
| Hydrochloric Acid SCHEMBL21073999 | 0.78 | CYP2D6 (0.50) | CYP2D6CYP3A4ALDH1A1CYP2C19TSHR | |
| SCHEMBL24475311 | 0.77 | TSHR (0.38) | CYP2D6CYP3A4ALDH1A1CYP2C19TSHR | |
| SCHEMBL25881815 | 0.75 | OPRM1 (0.40) | CYP2D6HRH3TLR9TLR8TLR7 | |
| SCHEMBL24233104 | 0.75 | TSHR (0.35) | CYP2D6CYP3A4TSHRCYP2C9HRH3 | |
| SCHEMBL29317410 | 0.74 | POLB (0.36) | HRH3TLR9TLR8TLR7L3MBTL3 | |
| Hydrochloric Acid SCHEMBL31097575 | 0.72 | CYP2D6 (0.45) | CYP2D6CYP3A4ALDH1A1CYP2C19TSHR | |
| SCHEMBL24233101 | 0.72 | POLB (0.36) | MEN1KMT2AHRH3TLR9TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |