Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 8/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22560635 | 0.91 | HRH3 (0.40) | POLBHRH3SMN1; SMN2TLR9TLR8 | |
| SCHEMBL29317410 | 0.87 | POLB (0.36) | POLBHRH3TLR9TLR8TLR7 | |
| SCHEMBL24233101 | 0.85 | POLB (0.36) | POLBHRH3TLR9TLR8TLR7 | |
| SCHEMBL25605624 | 0.83 | ACHE (0.50) | POLBHRH3TLR9TLR8TLR7 | |
| SCHEMBL25856312 | 0.83 | HRH3 (0.40) | POLBHRH3TLR9TLR8TLR7 | |
| SCHEMBL25856575 | 0.83 | NCF1 (0.37) | POLBHRH3SMN1; SMN2ACHECHRM5 | |
| SCHEMBL25027122 | 0.83 | NCF1 (0.37) | POLBHRH3SMN1; SMN2ACHECHRM5 | |
| SCHEMBL19312863 | 0.82 | POLB (0.36) | POLBHRH3ACHECHRM5ADRA2C | |
| SCHEMBL24480971 | 0.82 | CHRM5 (0.38) | POLBHRH3SMN1; SMN2ACHECHRM5 | |
| SCHEMBL25600510 | 0.82 | OPRL1 (0.39) | POLBTLR9TLR8TLR7ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |