SCHEMBL29317427

SCHEMBL29317427

Cc1cc(C(=O)CCC(=O)O)cc(C)c1C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.57
NR4A2 P43354 1/20 0.52
MEN1 O00255 1/20 0.50
USP5 P45974 1/20 0.47
ALDH1A1 P00352 2/20 0.47
CYP2C19 P33261 2/20 0.47
GAA P10253 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
CYP1A2 P05177 2/20 0.46
FFAR1 O14842 1/20 0.46
LMNA P02545 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HIF1A Q16665 1/20 0.46
NPSR1 Q6W5P4 1/20 0.45
HPGD P15428 1/20 0.45
HSD17B10 Q99714 1/20 0.45
HTT P42858 1/20 0.45
FABP4 P15090 1/20 0.42
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4085923 0.84 KMT2A (0.53) KMT2ANR4A2MEN1USP5ALDH1A1
SCHEMBL9861846 0.82 ALDH1A1 (0.53) KMT2ANR4A2MEN1USP5ALDH1A1
SCHEMBL5084680 0.81 KMT2A (0.64) KMT2ANR4A2MEN1USP5ALDH1A1
SCHEMBL11733812 0.80 KMT2A (0.53) KMT2ANR4A2MEN1USP5ALDH1A1
SCHEMBL8688169 0.80 KMT2A (0.53) KMT2ANR4A2MEN1USP5ALDH1A1
SCHEMBL5081102 0.80 KMT2A (0.63) KMT2ANR4A2MEN1USP5ALDH1A1
SCHEMBL9352415 0.79 KMT2A (0.50) KMT2ANR4A2MEN1USP5ALDH1A1
SCHEMBL8214726 0.77 KMT2A (0.59) KMT2ANR4A2MEN1USP5ALDH1A1
SCHEMBL10764064 0.76 KMT2A (0.58) KMT2ANR4A2MEN1USP5ALDH1A1
SCHEMBL11536711 0.76 KMT2A (0.58) KMT2ANR4A2MEN1USP5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239834-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS FUJIMOTO CHEMICALS CO., LTD., (JP) 2024-07-18 US disclosed
US-20240239833-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS FUJIMOTO CHEMICALS CO., LTD., (JP) 2024-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239834-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS ROS1, POLN, RNMT KMT2A 1962/4885NR4A2 296/4885MEN1 4209/4885
US-20240239833-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS ROS1, POLN, RNMT KMT2A 1962/4885NR4A2 296/4885MEN1 4209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.