Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1527147 | 0.85 | DNM1 (0.72) | DNM1KDM4EMEN1KMT2APAOX | |
| SCHEMBL15198294 | 0.84 | DNM1 (0.63) | DNM1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL1957975 | 0.83 | GAA (0.55) | DNM1MEN1KMT2AALDH1A1PAOX | |
| SCHEMBL23899001 | 0.83 | DNM1 (0.82) | DNM1KDM4EPAOXNAAATSHR | |
| SCHEMBL8773743 | 0.83 | DNM1 (0.76) | DNM1KDM4EPAOXNAAATSHR | |
| SCHEMBL766399 | 0.81 | DNM1 (0.64) | DNM1PAOXCYP2C9CYP2C19 | |
| SCHEMBL7523725 | 0.81 | DNM1 (0.64) | DNM1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7137887 | 0.81 | DNM1 (0.79) | DNM1KDM4EPAOXNAAATSHR | |
| Hydrochloric Acid SCHEMBL30387184 | 0.81 | DNM1 (0.60) | DNM1MEN1KMT2AALDH1A1HTT | |
| SCHEMBL11402225 | 0.79 | DNM1 (0.77) | DNM1KDM4EMEN1KMT2APAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146920-A1 | DRUG CONJUGATES FOR THE TREATMENT OF OCULAR DISORDERS | ASCENDIS PHARMA OPHTHALMOLOGY DIVISION A/S (DK) | 2024-07-11 | — | — | WO | disclosed |