Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.64 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1527147 | 0.88 | DNM1 (0.72) | DNM1PAOXKDM4EMEN1KMT2A | |
| SCHEMBL8773743 | 0.86 | DNM1 (0.76) | DNM1PAOXKDM4EALOX15NAAA | |
| SCHEMBL23899001 | 0.86 | DNM1 (0.82) | DNM1PAOXKDM4ENAAATSHR | |
| SCHEMBL13576204 | 0.85 | DNM1 (0.64) | DNM1PAOXKDM4EMEN1KMT2A | |
| SCHEMBL22694309 | 0.85 | PAOX (0.58) | DNM1PAOXKDM4EMEN1ALDH1A1 | |
| SCHEMBL7137887 | 0.84 | DNM1 (0.79) | DNM1PAOXKDM4ENAAATSHR | |
| SCHEMBL20438143 | 0.83 | DNM1 (0.65) | DNM1MEN1ALDH1A1KMT2ATDP1 | |
| SCHEMBL11402225 | 0.82 | DNM1 (0.77) | DNM1PAOXKDM4EMEN1KMT2A | |
| SCHEMBL29317564 | 0.81 | DNM1 (0.60) | DNM1PAOXKDM4EMEN1ALDH1A1 | |
| SCHEMBL24485546 | 0.81 | DNM1 (0.63) | DNM1PAOXKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380274-B1 | REACTING AN ORGANIC POLYISOCYANATE WITH A COMPOUND HAVING A REACTIVE HYDROGEN IN THE PRESENCE OF ALKOXY AMIDE COMPOUND AS CATALYST TO PRODUCE POLYURETHANE | AIR PRODUCTS AND CHEMICALS, INC. | 2002-04-30 | — | — | US | disclosed |
| EP-0799821-B1 | Process for the synthesis of polyurethane using reactive amine catalysts | CROMPTON CORP (US) | 2002-03-13 | — | — | EP | disclosed |
| US-6313346-B1 | Catalyst compositions for the production of polyurethanes | AIR PRODUCTS AND CHEMICALS, INC. | 2001-11-06 | — | — | US | disclosed |
| US-6153659-A | 3-{N-[2-(N',N'-dimethylamino ethoxy)ethyl]-N-methylamino}propionamide for the production of polyurethanes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2000-11-28 | — | — | US | disclosed |
| EP-1038894-A2 | New catalyst compositions for the production of polyurethanes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2000-09-27 | — | — | EP | disclosed |
| EP-1038895-A2 | 3- (N-(2-(N',N'-Dimethylamino Ethoxy)Ethyl) -N-Methylamino) Propionamide for the production of polyurethanes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2000-09-27 | — | — | EP | disclosed |
| US-6037496-A | CATALYZES THE REACTION BETWEEN AN ISOCYANATE AND WATER IN THE PRODUCTION OF FOAMED POLYURETHANES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2000-03-14 | — | — | US | disclosed |