Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12445299 | 0.86 | CRHBP (0.39) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL29321029 | 0.85 | — | — | |
| SCHEMBL18878034 | 0.84 | CRHBP (0.40) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL20434849 | 0.81 | CRHBP (0.37) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL20434855 | 0.79 | CRHBP (0.35) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL23697615 | 0.77 | GRIN2D (0.33) | — | |
| SCHEMBL680047 | 0.75 | CRHBP (0.39) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL19498154 | 0.73 | CRHBP (0.32) | CRHBPCRHR2 | |
| SCHEMBL12127018 | 0.72 | CRHBP (0.38) | CRHBPCRHR2ALDH1A1 | |
| SCHEMBL21341490 | 0.72 | GRIN2D (0.33) | CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | PFIZER INC. (US) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | HSD17B13, HSD17B3, HSD17B1 | CRHBP 827/4885CRHR2 2038/4885ALDH1A1 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.