Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GNAI3 | P08754 | 9/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 9/20 | 0.48 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23594627 | 0.98 | NPC1 (0.50) | NPC1GNAI3GNAI1GNAO1ITGB3 | |
| SCHEMBL23922141 | 0.94 | NPC1 (0.51) | NPC1GNAI3GNAI1GNAO1ITGB3 | |
| SCHEMBL12793198 | 0.87 | CYP2D6 (0.46) | NPC1GNAI3GNAI1GNAO1ITGB3 | |
| SCHEMBL22147051 | 0.86 | NPC1 (0.50) | NPC1GNAI3GNAI1GNAO1ITGB3 | |
| SCHEMBL24926179 | 0.86 | NPC1 (0.50) | NPC1GNAI3GNAI1GNAO1ITGB3 | |
| SCHEMBL23594493 | 0.85 | NPC1 (0.46) | NPC1GNAI3GNAI1GNAO1ITGB3 | |
| SCHEMBL23594339 | 0.84 | NPC1 (0.49) | NPC1GNAI3GNAI1GNAO1ITGB3 | |
| SCHEMBL23594270 | 0.84 | NPC1 (0.49) | NPC1GNAI3GNAI1GNAO1ITGB3 | |
| SCHEMBL13964621 | 0.84 | GNAI3 (0.62) | NPC1GNAI3GNAI1GNAO1CYP2D6 | |
| SCHEMBL17471168 | 0.83 | NPC1 (0.50) | NPC1GNAI3GNAI1GNAO1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | PFIZER INC. (US) | 2024-07-18 | — | — | US | disclosed |
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | PFIZER INC. (US) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | HSD17B13, HSD17B3, HSD17B1 | NPC1 999/4885GNAI3 3127/4885GNAI1 4093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.