Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 9/20 | 0.50 |
| ▸ | MGLL | Q99685 | 8/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29321296 | 0.82 | MGLL (0.41) | EPHX2MGLLALDH1A1 | |
| SCHEMBL20469333 | 0.82 | EPHX2 (0.52) | EPHX2MGLLCYP3A4 | |
| SCHEMBL22021873 | 0.80 | GRIN2D (0.35) | EPHX2MGLL | |
| SCHEMBL23083347 | 0.80 | — | — | |
| SCHEMBL20469335 | 0.79 | EPHX2 (0.52) | EPHX2MGLL | |
| SCHEMBL29317645 | 0.78 | GRIN2D (0.36) | — | |
| SCHEMBL27009205 | 0.78 | EPHX2 (0.45) | EPHX2MGLLCYP3A4ALDH1A1HTT | |
| SCHEMBL17281958 | 0.77 | — | — | |
| SCHEMBL21140961 | 0.77 | KCNH2 (0.32) | — | |
| SCHEMBL13093540 | 0.77 | KCNH2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | PFIZER INC. (US) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | HSD17B13, HSD17B3, HSD17B1 | EPHX2 949/4885MGLL 536/4885CYP3A4 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.