Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28417328 | 0.81 | PTGS2 (0.44) | PTGS2MALT1ALDH1A1 | |
| SCHEMBL1497714 | 0.81 | PTGS2 (0.44) | PTGS2POLBALDH1A1 | |
| SCHEMBL28441891 | 0.80 | NPC1 (0.38) | PTGS2ALDH1A1 | |
| SCHEMBL15920816 | 0.70 | PGR (0.40) | CA1CA2PGR | |
| SCHEMBL16076085 | 0.70 | PTGS2 (0.39) | PTGS2POLBGAAMGAT2ALDH1A1 | |
| SCHEMBL30790602 | 0.69 | PTGS2 (0.48) | PTGS2ALDH1A1 | |
| SCHEMBL1700136 | 0.69 | PTGS2 (0.48) | PTGS2POLBALDH1A1 | |
| SCHEMBL24170804 | 0.68 | NPC1 (0.38) | PTGS2ALDH1A1 | |
| SCHEMBL15920855 | 0.67 | PGR (0.35) | BUB1PGR | |
| SCHEMBL1958631 | 0.66 | PTGS2 (0.55) | PTGS2POLBCYP11B2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |