Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | PRKDC | P78527 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1700335 | 0.75 | SLC6A3 (0.46) | KDM4EALDH1A1MAPTMAPK1PTGS2 | |
| SCHEMBL1958644 | 0.75 | PTGS2 (0.50) | KDM4EALDH1A1MAPTMAPK1PTGS2 | |
| SCHEMBL1957401 | 0.74 | SLC6A3 (0.47) | KDM4EALDH1A1PTGS2PTGS1HSD17B10 | |
| SCHEMBL1956409 | 0.74 | SLC6A3 (0.47) | KDM4EALDH1A1PTGS2PTGS1HSD17B10 | |
| SCHEMBL1957404 | 0.74 | SLC6A3 (0.47) | KDM4EALDH1A1PTGS2PTGS1HSD17B10 | |
| SCHEMBL17460596 | 0.71 | ERN1 (0.41) | — | |
| SCHEMBL1956774 | 0.71 | PTGS2 (0.38) | KDM4EALDH1A1MAPTMAPK1PTGS2 | |
| SCHEMBL29374908 | 0.70 | — | — | |
| SCHEMBL1699985 | 0.70 | MAPT (0.41) | KDM4EALDH1A1MAPTMAPK1PTGS2 | |
| SCHEMBL15539299 | 0.69 | PTGS2 (0.44) | KDM4EALDH1A1MAPTMAPK1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |