Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.32 |
| ▸ | KMO | O15229 | 2/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30075034 | 0.90 | PTGS2 (0.33) | PTGS2FASNPTGS1CES1GRM2 | |
| SCHEMBL16037793 | 0.90 | PTGS2 (0.33) | PTGS2FASNPTGS1CES1GRM2 | |
| SCHEMBL29319415 | 0.85 | PTGS2 (0.33) | PTGS2FASNPTGS1GRM2KMO | |
| SCHEMBL15921407 | 0.80 | ERN1 (0.43) | — | |
| SCHEMBL1497714 | 0.77 | PTGS2 (0.44) | PTGS2PTGS1 | |
| SCHEMBL29320708 | 0.76 | KMT2A (0.36) | PTGS2FASNGRM2KMO | |
| SCHEMBL15920816 | 0.76 | PGR (0.40) | — | |
| SCHEMBL29750072 | 0.75 | FASN (0.31) | PTGS2FASNPTGS1CES1GRM2 | |
| SCHEMBL15920855 | 0.75 | PGR (0.35) | — | |
| SCHEMBL16039916 | 0.74 | FASN (0.35) | PTGS2FASNPTGS1CES1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |