Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 7/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.41 |
| ▸ | BCL9 | O00512 | 3/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29318865 | 0.94 | DRD3 (0.41) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL29318781 | 0.86 | BCL9 (0.41) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL29320229 | 0.83 | PPARA (0.42) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL29318790 | 0.82 | BCL9 (0.44) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL29318826 | 0.81 | DRD3 (0.39) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL29318807 | 0.80 | DRD3 (0.40) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL29319476 | 0.78 | DRD3 (0.35) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL29322028 | 0.74 | DRD2 (0.41) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL29319218 | 0.74 | BCL9 (0.39) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL29320372 | 0.73 | BCL9 (0.41) | DRD3DRD2DRD4DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145931-A1 | SMALL MOLECULE INHIBITOR FOR β-CATENIN/BCL9 PROTEIN-PROTEIN INTERACTION AND USE THEREOF | 上海医药工业研究院有限公司 | 2024-07-11 | — | — | WO | disclosed |