Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 11/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.40 |
| ▸ | P2RY11 | Q96G91 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19503356 | 0.81 | ADCY5 (0.48) | P2RY1ADORA2AENPP1P2RY12 | |
| SCHEMBL29318562 | 0.81 | ADCY5 (0.48) | P2RY1ADORA2AENPP1P2RY12 | |
| SCHEMBL11363312 | 0.78 | ADORA2A (0.58) | P2RY1ADORA2AENPP1P2RY12BLM | |
| SCHEMBL19503474 | 0.73 | AHCY (0.49) | P2RY1ENPP1P2RY12LMNABLM | |
| SCHEMBL19464993 | 0.71 | ADORA3 (0.69) | P2RY1ADORA2A | |
| SCHEMBL22933143 | 0.71 | ADORA3 (0.69) | P2RY1ADORA2A | |
| SCHEMBL25566750 | 0.71 | ADORA3 (0.69) | P2RY1ADORA2A | |
| SCHEMBL19464998 | 0.71 | ADORA3 (0.69) | P2RY1ADORA2A | |
| SCHEMBL598755 | 0.71 | ADORA2A (0.62) | ADORA2ABLM | |
| SCHEMBL12330956 | 0.70 | AHCY (0.56) | P2RY1ENPP1P2RY12P2RY11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445368-B1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS INC (US) | 2024-07-17 | — | — | EP | disclosed |