Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 6/20 | 0.46 |
| ▸ | DRD2 | P14416 | 5/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29320372 | 0.78 | BCL9 (0.41) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL29320312 | 0.77 | BCL9 (0.39) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL29318352 | 0.77 | BCL9 (0.65) | — | |
| SCHEMBL29319266 | 0.76 | DRD3 (0.41) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL29319368 | 0.76 | BCL9 (0.55) | — | |
| SCHEMBL29320294 | 0.76 | BCL9 (0.39) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL29320518 | 0.75 | BCL9 (0.37) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL29318781 | 0.75 | BCL9 (0.41) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL29319614 | 0.73 | BCL9 (0.39) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL29319057 | 0.70 | BCL9 (0.38) | DRD3DRD2DRD4DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145931-A1 | SMALL MOLECULE INHIBITOR FOR β-CATENIN/BCL9 PROTEIN-PROTEIN INTERACTION AND USE THEREOF | 上海医药工业研究院有限公司 | 2024-07-11 | — | — | WO | disclosed |