SCHEMBL29319266 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	DRD3	P35462	7/20	0.41

▸	DRD2	P14416	6/20	0.41

▸	BCL9	O00512	2/20	0.41

▸	CTNNB1	P35222	2/20	0.41

▸	DRD4	P21917	4/20	0.40

▸	DRD1	P21728	2/20	0.40

▸	DRD5	P21918	2/20	0.40

▸	HTR7	P34969	1/20	0.39

▸	SIGMAR1	Q99720	3/20	0.36

▸	NFKB1	P19838	1/20	0.36

▸	PRCP	P42785	1/20	0.36

▸	EBP	Q15125	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29319337	0.76	DRD3 (0.46)	DRD3DRD2DRD4DRD1DRD5
SCHEMBL30350376	0.74	BCL9 (0.71)	BCL9CTNNB1
SCHEMBL29318351	0.74	BCL9 (0.71)	BCL9CTNNB1
SCHEMBL29319293	0.72	BCL9 (0.59)	BCL9CTNNB1
SCHEMBL29319591	0.72	BCL9 (0.39)	DRD3DRD2BCL9CTNNB1DRD4
SCHEMBL29318865	0.66	DRD3 (0.41)	DRD3DRD2BCL9CTNNB1DRD4
SCHEMBL29320372	0.66	BCL9 (0.41)	DRD3DRD2BCL9CTNNB1DRD4
SCHEMBL29318885	0.65	DRD3 (0.42)	DRD3DRD2BCL9CTNNB1DRD4
SCHEMBL23599275	0.64	SMN1; SMN2 (0.44)	BCL9CTNNB1
SCHEMBL29319655	0.64	DRD2 (0.59)	DRD3DRD2DRD4DRD1DRD5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024145931-A1	SMALL MOLECULE INHIBITOR FOR β-CATENIN/BCL9 PROTEIN-PROTEIN INTERACTION AND USE THEREOF	上海医药工业研究院有限公司	2024-07-11	—	—	WO	disclosed