SCHEMBL20986908

SCHEMBL20986908

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nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.45
SLC1A2 P43004 1/20 0.45
SLC1A1 P43005 1/20 0.45
TSHR P16473 2/20 0.38
CYP2C9 P11712 1/20 0.35
PDE4A P27815 1/20 0.35
TP53 P04637 1/20 0.31
PGD P52209 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12610770 1.00 SLC1A3 (0.45) SLC1A3SLC1A2SLC1A1TSHRCYP2C9
SCHEMBL12610806 0.86 SLC1A3 (0.48) SLC1A3SLC1A2SLC1A1TSHRTP53
SCHEMBL12610812 0.86 SLC1A3 (0.48) SLC1A3SLC1A2SLC1A1TSHRTP53
SCHEMBL22688963 0.84 TSHR (0.43) SLC1A3SLC1A2SLC1A1TSHRCYP2C9
SCHEMBL29455702 0.84 TSHR (0.43) SLC1A3SLC1A2SLC1A1TSHRCYP2C9
SCHEMBL11503365 0.82 SLC1A3 (0.48) SLC1A3SLC1A2SLC1A1TSHRCYP2C9
SCHEMBL2932038 0.82 SLC1A3 (0.48) SLC1A3SLC1A2SLC1A1TSHRCYP2C9
SCHEMBL10146952 0.82 TSHR (0.41) SLC1A3SLC1A2SLC1A1TSHRCYP2C9
SCHEMBL28912115 0.79 TSHR (0.35) SLC1A3SLC1A2SLC1A1TSHRCYP2C9
SCHEMBL3922086 0.79 TSHR (0.35) SLC1A3SLC1A2SLC1A1TSHRCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667784-B2 Copolymers including cinchona alkaloid components and one or more acrylamide or acrylate containing components, complexes containing the same, and methods of using the REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2023-06-06 US disclosed
US-20190153212-A1 COPOLYMERS INCLUDING CINCHONA ALKALOID COMPONENTS AND ONE OR MORE ACRYLAMIDE OR ACRYLATE CONTAINING COMPONENTS, COMPLEXES CONTAINING THE SAME, AND METHODS OF USING THE SAME REGENTS OF THE UNIVERSITY OF MINNESOTA 2019-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667784-B2 Copolymers including cinchona alkaloid components and one or more acrylamide or acrylate containing components, complexes containing the same, and methods of using the BRCA1, DCLRE1A, NIPSNAP3A SLC1A3 1082/4885SLC1A2 1194/4885SLC1A1 489/4885
US-20190153212-A1 COPOLYMERS INCLUDING CINCHONA ALKALOID COMPONENTS AND ONE OR MORE ACRYLAMIDE OR ACRYLATE CONTAINING COMPONENTS, COMPLEXES CONTAINING THE SAME, AND METHODS OF USING THE SAME PCNA, NCLN, CROCC SLC1A3 1366/4885SLC1A2 1727/4885SLC1A1 752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.