Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 12/20 | 0.42 |
| ▸ | RAB9A | P51151 | 12/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10129490 | 0.82 | SSTR4 (0.48) | SSTR4PTGS1PTGS2NPC1RAB9A | |
| SCHEMBL30339144 | 0.79 | RAB9A (0.46) | SSTR4PTGS1PTGS2NPC1RAB9A | |
| SCHEMBL9796679 | 0.79 | SSTR4 (0.46) | SSTR4PTGS1PTGS2NPC1RAB9A | |
| SCHEMBL18517250 | 0.77 | NPC1 (0.48) | SSTR4PTGS1PTGS2NPC1RAB9A | |
| SCHEMBL161950 | 0.75 | RAB9A (0.49) | SSTR4PTGS1PTGS2NPC1RAB9A | |
| SCHEMBL22333551 | 0.74 | SSTR4 (0.45) | SSTR4PTGS1PTGS2NPC1RAB9A | |
| SCHEMBL21239943 | 0.74 | SSTR4 (0.45) | SSTR4PTGS1PTGS2NPC1RAB9A | |
| SCHEMBL23562883 | 0.72 | RAB9A (0.45) | SSTR4PTGS1PTGS2NPC1RAB9A | |
| SCHEMBL15979317 | 0.72 | SSTR4 (0.44) | SSTR4PTGS1PTGS2NPC1RAB9A | |
| SCHEMBL9968616 | 0.71 | NPC1 (0.54) | NPC1RAB9AKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | PFIZER INC. (US) | 2024-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238425-A1 | HSD17B13 Inhibitors and/or Degraders | HSD17B13, HSD17B3, HSD17B1 | SSTR4 2086/4885PTGS1 1514/4885PTGS2 1680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.