Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19386132 | 1.00 | TSHR (0.35) | TSHRKDM4ETP53EGLN1EGLN3 | |
| SCHEMBL2932866 | 1.00 | TSHR (0.35) | TSHRKDM4ETP53EGLN1EGLN3 | |
| SCHEMBL2932087 | 1.00 | TSHR (0.35) | TSHRKDM4ETP53EGLN1EGLN3 | |
| SCHEMBL28815581 | 0.83 | KDM4E (0.32) | TSHRKDM4E | |
| SCHEMBL13176798 | 0.81 | KDM4E (0.31) | TSHRKDM4E | |
| SCHEMBL1533836 | 0.81 | — | — | |
| SCHEMBL1588 | 0.81 | — | — | |
| SCHEMBL28169695 | 0.81 | TSHR (0.41) | TSHRKDM4ETP53EGLN1EGLN3 | |
| SCHEMBL1589 | 0.81 | — | — | |
| SCHEMBL10339835 | 0.78 | TSHR (0.39) | TSHRKDM4ETP53EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114990036-B | Method for producing 2-pyrone-4, 6-dicarboxylic acid by whole cell catalysis | 中国科学院天津工业生物技术研究所 | 2024-06-04 | — | — | CN | claimed |
| CN-115466706-A | Escherichia coli recombinant strain for producing 2-pyrone-4,6-dicarboxylic acid and construction method and application thereof | 中国科学院天津工业生物技术研究所 | 2022-12-13 | — | — | CN | claimed |
| CN-114990036-A | Method for producing 2-pyrone-4,6-dicarboxylic acid through whole-cell catalysis | 中国科学院天津工业生物技术研究所 | 2022-09-02 | — | — | CN | claimed |
| CN-115466706-B | Recombinant strain of escherichia coli for producing 2-pyrone-4, 6-dicarboxylic acid, construction method and application thereof | 中国科学院天津工业生物技术研究所 | 2026-02-13 | — | — | CN | disclosed |
| US-20250361531-A1 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS | AGAIN BIO APS (DK) | 2025-11-27 | — | — | US | disclosed |
| US-12312627-B2 | Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds | GENOMATICA, INC. (US) | 2025-05-27 | — | — | US | disclosed |
| CN-114990036-B | Method for producing 2-pyrone-4, 6-dicarboxylic acid by whole cell catalysis | 中国科学院天津工业生物技术研究所 | 2024-06-04 | — | — | CN | disclosed |
| CN-114990036-B | Method for producing 2-pyrone-4, 6-dicarboxylic acid by whole cell catalysis | 中国科学院天津工业生物技术研究所 | 2024-06-04 | — | — | CN | disclosed |
| CN-118006533-A | Recombinant escherichia coli for producing 2-pyrone-4, 6-dicarboxylic acid and application thereof | 中国科学院天津工业生物技术研究所 | 2024-05-10 | — | — | CN | disclosed |
| US-11932845-B2 | Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds | GENOMATICA, INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-20230134936-A1 | COMPOSITIONS AND METHODS FOR THE BIOSYNTHESIS OF 1,4-BUTANEDIOL AND ITS PRECURSORS | GENOMATICA INC (US) | 2023-05-04 | — | — | US | disclosed |
| CN-115484867-A | Transducer, nanoparticle transducer apparatus and system, and related methods of use | 华盛顿大学 | 2022-12-16 | — | — | CN | disclosed |
| CN-115466706-A | Escherichia coli recombinant strain for producing 2-pyrone-4,6-dicarboxylic acid and construction method and application thereof | 中国科学院天津工业生物技术研究所 | 2022-12-13 | — | — | CN | disclosed |
| CN-115466706-A | Escherichia coli recombinant strain for producing 2-pyrone-4,6-dicarboxylic acid and construction method and application thereof | 中国科学院天津工业生物技术研究所 | 2022-12-13 | — | — | CN | disclosed |
| CN-114990036-A | Method for producing 2-pyrone-4,6-dicarboxylic acid through whole-cell catalysis | 中国科学院天津工业生物技术研究所 | 2022-09-02 | — | — | CN | disclosed |
| CN-114990036-A | Method for producing 2-pyrone-4,6-dicarboxylic acid through whole-cell catalysis | 中国科学院天津工业生物技术研究所 | 2022-09-02 | — | — | CN | disclosed |
| US-11401534-B2 | Microorganisms for the production of 1,4- butanediol and related methods | GENOMATICA, INC. (US) | 2022-08-02 | — | — | US | disclosed |
| US-11371046-B2 | Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors | GENOMATICA, INC. (US) | 2022-06-28 | — | — | US | disclosed |
| WO-2017165689-A2 | CONVERSION OF BIOMASS TO USEFUL INTERMEDIATES | ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) | 2017-09-28 | — | — | WO | disclosed |
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250361531-A1 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS | HSD17B10, HSD17B12, HADHB | TSHR 4441/4885KDM4E 374/4885TP53 4590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.