SCHEMBL29322296

SCHEMBL29322296

O=C(CBr)c1cccc(Br)c1O

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 5/20 0.52
GSK3B P49841 10/20 0.42
HPGDS O60760 1/20 0.38
MAOB P27338 1/20 0.38
AKR1C4 P17516 1/20 0.37
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37
AKR1C1 Q04828 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HSD17B10 Q99714 1/20 0.37
PRNP P04156 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9753566 0.84 MAOB (0.38) PTPN1MAOBAKR1C4AKR1C3AKR1C2
SCHEMBL27673463 0.82 F2R (0.45) MAOBALDH1A1HPGDSMN1; SMN2HSD17B10
SCHEMBL166468 0.81 PTPN1 (0.57) PTPN1GSK3BHPGDSALDH1A1HPGD
SCHEMBL29758522 0.81 PTPN1 (0.57) PTPN1GSK3BHPGDSALDH1A1HPGD
SCHEMBL8740774 0.81 PTPN1 (0.57) PTPN1GSK3BHPGDSALDH1A1HPGD
SCHEMBL9708883 0.80 ALDH1A1 (0.52) PTPN1GSK3BALDH1A1HPGDSMN1; SMN2
SCHEMBL22051489 0.78 PTPN1 (0.50) PTPN1GSK3BHPGDSMAOBALDH1A1
SCHEMBL4519224 0.78 PTPN1 (0.65) PTPN1GSK3BHPGDSALDH1A1HPGD
SCHEMBL30961290 0.78 PTPN1 (0.50) PTPN1GSK3BHPGDSMAOBALDH1A1
SCHEMBL31619208 0.78 ALDH1A1 (0.60) PTPN1GSK3BALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400499-A1 GLUTARIMIDE COMPOUND AND USE THEREOF Medshine Discovery Inc. (CN) 2024-07-17 EP disclosed